Destroying the messenger

Destroying the messenger

Big mammals have big (or slow) cells C ells use two basic strategies to adapt to the size of the organism in which they reside, say Van Savage and colleagues. Depending on how often they divide, comparable cells in a mouse and an elephant differ in either metabolic rate or cell volume, but usually not both. The need for such adaptation stems from simple geometry. As body volume increases, surfa...

Destroying Civilization, Destroying Nature

Destroying c-jun Messenger: New Insights into Biological Mechanisms of DNAzyme Function

The study by Cai and co-workers provided novel insights into the mechanism of action of DNAzymes. Dz13 rendered c-jun mRNA unstable, reduced growth factor expression and increased apoptosis in the tumors without apparent induction of oxidative stress. Interestingly, Dz13-mediated tumor decay was more profound in immunocompetent mice syngeneic to the tumor compared with immunocompromised animals...

The Messenger of God, Managing the Quarrels in Medina

Conflict and quarrel may be counted essential for human societies. In some cases, lack of wise management leads quarrels to crisis in such a way that its foundation comes to be destroyed. The importance of the problem has led scholars in the field of management to deal with it and study to find a solution. This paper has studied the solutions of the Prophet for the quarrels of peoples in Medina...

Permutations Destroying Arithmetic Structure

Given a linear form C1X1 + · · · + CnXn, with coefficients in the integers, we characterize exactly the countably infinite abelian groups G for which there exists a permutation f that maps all solutions (α1, . . . , αn) ∈ Gn (with the αi not all equal) to the equation C1X1+ · · ·+CnXn = 0 to non-solutions. This generalises a result of Hegarty about permutations of an abelian group avoiding arit...